No, but certain episodes get me tired.
I've seen every episode at least 5 times (With the exceptions of: Safe Deposit Krabs, Are You Happy Now?, SpongeBob you're fired, and maybe two or three others).
This is my watching schedule:
At home, I'll watch episodes I haven't seen on cable once. If there's a certain episode that I really want to watch again, or an episode a friend wants to see, I'll stream it through Amazon Instant Video on a Roku device.
At my grandparents house, I watch reruns and DVDs all the time (around 6 episodes per day- I know, it's unhealthy).
Anywhere else, I usually don't have time to watch SpongeBob. Sometimes I'm able to catch an episode or two in my hotel room.