Judging from the ads, it doesn't seem like this show has any substance to it, which is a problem for me as I like to watch shows with decent plots and good characters. Also, when I saw the ads with my friends, they thought that Uncle Grandpa himself was annoying and that he looked "punchable." (They were probably joking, though.)
I'll see if I can find an episode on the Internet since they started airing them, but I don't have very high expectations.